Description

Annexin A1 (ANXA1) is a membrane protein that plays a role in innate and adaptive immunity by controlling the biosynthesis of inflammation, prostaglandins, and leukotriene mediators. This target is overexpressed in 97% of all samples from patients with with hairy cell leukemia, and is absent in other B-cell lymphomas. High ANXA1 expression is frequently associated with advanced stage esophageal and esophagogastric junction adenocarcinoma, and is also linked to advanced and metastatic disease states.

Mouse  Anti-Annexin A1 antibody

Volum : 0.1ml

Reactivity : Mouse, Rat, Human，

Applications :

IHC=1:100-1:200

WB=1:500-1:2000

ICC/IF=1:100-1:200

Anti-gen synonyms :.Recombinant full length protein corresponding to Human Annexin A1 aa 1-346.
Sequence:

MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAA LHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKAL TGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIR DINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLAD SDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNK VLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN

Uniprot No. :P043083

Host : Mouse.

Clonality : Monoclonal

Isotopes : IgG

Concentration : 1mg/1ml

Purification :affinity purified by Protein A

Storage : May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Research Area : Cellular Immunology Signal transduction