Description

Background: BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.
Host species/Isotype : Rabbit/IgG
Species reactivity : Human, Mouse, Rat
Immunogen : KLH conjugated synthetic peptide derived from human BMP2:341-396/396.
Storage instructions : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Concentration : 1mg/ml
Purity : affinity purified by Protein A
Clonality : Polyclonal
Molecular weight : 13/44kDa
Tested applications:
WB=1:500-2000
ELISA=1:500-1000
IHC-P=1:100-500
IHC-F=1:100-500
ICC=1:100-500
IF=1:100-500