Description

Fibroblast activation protein, alpha; 170 kDa melanoma membrane bound gelatinase; 170 kDa melanoma membrane-bound gelatinase; DPPIV; FAP; Fibroblast activation protein alpha; Integral membrane serine protease; SEPR_HUMAN; Prolyl endopeptidase FAP; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl Peptidase FAP; FAPalpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; Serine integral membrane protease; SIMP; Surface-expressed protease; Seprase; Antiplasmin-cleaving enzyme FAP, soluble form;
Concentration: 1mg/ ml
Purity: ≥96%
Endotoxin level: < 1.000 Eu / μg
Purification method: HPLC
Application: SDS-PAGE, Western blot, ELISA
Biological activity,immunology research
Save: -20 ° C
Shelf life: 2 years
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. Thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. alternative spliced ​​transcript variants encoding different isoforms have been found for this gene.

Specification:1mg