Description

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.

Host species/Isotype:Rabbit/IgG

Species reactivity: Human, Mouse,Rat

Immunogen:KLH conjugated synthetic peptide derived from human S100.

Storage instructions:Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Concentration:1mg/ml

Purity:affinity purified by Protein A

Clonality:Monoclonal

Molecular weight:10kDa

Tested applications:ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 ,not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.